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Congratulations to

Kaleigh Young

Arts & Sciences

Biology

Honors Thesis Faculty Advisor: Thomas Fondy

Thesis Title:

The Effect of Sequential Low-Frequency Ultrasonic Treatments on the Lytic and Non-Lytic Damage In Vitro of U937 Human Myelogenous Leukemia

My project focuses on treating leukemia in a physical manner rather than a chemical manner which is the basis for chemotherapy. Human leukemia cells, U937, are exposed to low-frequency ultrasound, or sound waves, at 20 kHz and 40 kHz frequencies, both separately and in combination. After the cells are exposed to the sonication, measurements are taken to determine if the cells’ membranes were disrupted creating cellular death or died in another manner. This research is important because it allows for a less detrimental treatment of leukemia, and eventually other cancers, that can prevent the horrific side effects that can be seen with chemotherapy. I would like to thank Dr. Thomas Fondy, Thomas Stack Jr, Dr. Jennifer Cook, and Dr. Scott Erdman for their help and continuous support with this project.

Links to Project Materials:

https://files.emailmeform.com/742180/tjOQSibw/Honors%20Thesis%20Project%20.docx

Additional support provided by: Thomas Fondy Research Fund

 

College of Arts & Sciences 2020, Natural Science & Engineering Projects 2020, 2020